Bioinformatics Scientist (100%), per Winter/Spring 2019

LocationZurich, Zurich region, Switzerland

Your Mission

ETH Zurich is one of the world’s leading universities specialising in science and technology. It is renowned for its excellent education, its cutting-edge fundamental research and its efforts to put new knowledge and innovations directly into practice. The laboratory of Genome Biology (Prof. Jacob Corn) develops genome editing technologies to explore biological questions and develop potential cures for genetic disorders. They are part of the National Center of Competence in Research in RNA and Disease (NCCR-RD), which is working to advance understanding of RNA processing and surveillance, plus identify disease mechanisms resulting from aberrant RNA function. To serve as a hands-on bioinformatics expert, the Corn group and NCCR-RD are seeking a

You will primarily report to Professor Jacob Corn, head of the Genome Biology group at ETH Zurich, and will work with NCCR-RD laboratories throughout Switzerland. A successful applicant will be a highly collaborative, self-motivated researcher with deep expertise in modern next-generation sequencing output and analysis. You will provide expertise in computational genomics for the analysis of next-gen sequencing data and its integration with public databases such as TCGA, CCLE, and ENCODE. In addition, you provide consultation to researchers to design experiments, perform data analysis, and trouble-shooting. You will use computational infrastructure and software packages, including workstations, high- performance computing clusters, and cloud/national infrastructure platforms and will effectively communicate with NCCR-RD laboratories. You will also work as part of a team to draft manuscripts and prepare presentations.

A Ph.D. or equivalent degree in Bioinformatics, Molecular Biology, Statistics, Computer Science or related field is required. Applicants must have experience working with next-generation sequencing data, such as: functional genomics screening, quantification of alleles from amplicon sequencing, lineage barcoding, single cell and bulk RNA-Seq, ChIP-seq, high-throughput sequence analysis, genome variant analysis, and extensive collaborative work with wet-lab researchers. You bring along experience working with a subset of standard bioinformatics, statistics, and analytical tools and sufficient knowledge of UNIX/Linux to manage a system and interact with system administrators and support staff. Other required qualifications are advanced skills in scripting or programming languages, preferably Python, and the ability to communicate effectively in a highly diverse, cross-disciplinary environment.

Preferred Qualifications are experience in analyzing genome editing experiments, genomic data exploration, visualization, and figure preparation for publications, ability to complete and describe projects, demonstrated for example by journal articles and/or preprints and as well software/pipeline creation and maintenance, version control, reproducible workflows. A successful applicant will be a highly collaborative, self-motivated researcher with deep expertise in modern next-generation sequencing output and analysis. Familiarity with spoken and written English is requested.

The position is located at the Institute of Molecular Health Sciences  at the Hönggerberg Campus of ETH Zurich, a world-leading institution in basic and applied research.

In your application, please refer to
and reference  JobID 42033.